The highly regarded translational seminar series, “The ABC of Viral Hepatitis – From Translational Research to Clinical Practice,” was successfully conducted in its second year, building on the success of its inaugural term. This series continues to bridge the gap between research and clinical practice, fostering collaboration essential for the effective translation of scientific discoveries into real-world healthcare solutions. Focused on hepatitis, the seminar series examines the steps crucial for successful translation, including cutting-edge research findings, insights from current clinical studies, practical clinical experiences, and future-oriented therapeutic developments. As in its first year of the series, the seminars provided valuable perspectives and facilitated productive exchanges between researchers and clinicians. Additionally, the series aims to enhance long-term collaboration, driving innovation and improving outcomes for patients affected by hepatitis, as well as enhancing understanding and cooperation within the field.

The recent lectures featured prominent European virologists, immunologists, and hepatologists, highlighting the importance of scientific exchange between researchers and clinicians.

Lecture 1: Clinical Application of Gene-Modified HBV-Specific T Cells for Treatment of HBV-Induced HCC

On November 25, 2024, Dr. Karin Wisskirchen from SCG Cell Therapy GmbH, Germany, delivered a hybrid lecture titled “Clinical application of gene-modified HBV-specific T cells for treatment of HBV-induced HCC.” This lecture presented exciting and far-reaching findings, particularly regarding the potential clinical application of scientific data for treating hepatocellular carcinoma (HCC). Following the presentation, there was an extensive and intense discussion session, reflecting the high level of interest and engagement from the audience.

Lecture 2: Adapting to Life in the Human Liver: A T Cell Perspective

The second lecture, also conducted in a hybrid format, was held on December 16, 2024, by Dr. Laura Pallett from the UCL Institute of Immunity and Transplantation, London, England. Her lecture, titled “Adapting to life in the human liver: a T cell perspective,” provided deep and comprehensive immunological insights into the role of T cells in the liver. This presentation also concluded with a lively scientific discussion, underscoring the dynamic exchange of ideas and knowledge.

These lectures exemplify the seminar series’ commitment to fostering meaningful scientific dialogue and collaboration, ultimately aiming to translate research into tangible clinical advancements.